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帕金森综合征的鉴别诊断较难,有时仅根据临床表现不能区别原发性脑干 Lewy 体性帕金森病与纹状体黑质变性,帕金森病者对最大耐受剂量的左旋多巴的治疗反应总是不变的,而纹状体黑质变性则很不一致。许多其他帕金森综合征病人,如进行性核上性麻痹综合征(Steele/Richardson/Olszewski syn-drome,SRO)、肝豆状核变性综合征(Wilson 病)、皮质基底变性、脑血管疾病引起的下半身帕金森综合征及弥漫性 Lewy 体性痴呆等应用左旋多巴大多无效或反而令病情加重。此外,帕金森病患者长期服左旋多巴后可能出现对该药失效。因此,需要一种快
The differential diagnosis of Parkinson’s disease more difficult, and sometimes only based on clinical manifestations can not distinguish between primary brain stem Lewy Parkinson’s disease and striatonigral degeneration, Parkinson’s disease on the maximum tolerated dose of levodopa Treatment response is always the same, while striatum degeneration is very inconsistent. Many other Parkinson’s patients, such as Steele / Richardson / Olszewski syn-drome (SRO), Wilson’s disease, corticobasal degeneration, and cerebrovascular disease Lower half of Parkinson’s disease and diffuse Lewy body dementia and other applications of mostly ineffective levodopa or on the contrary make the disease worse. In addition, patients with Parkinson’s disease long-term service of levodopa may appear to be invalid. So, need a fast