Effects of AT1 Antagonist on MMP2, MMP9 Expression and Collagen Remodeling in Left Ventricle of Rabb

• 作 者: 王军奎 崔长琮 姚青海 姚晓伟 崔翰斌
• 机 构: DepartmentofCardiology
• 出 处: South China Journal of Cardiology
• 发表日期: 2003年1期
• 关键词: 缬沙坦 金属基质蛋白-2 金属基质蛋白-9 胶原质 左心室 心脏疾病 Valsartan Collagen fibers Ventricule remodeli

Objectives To study the effects of AT1 antagonist on MMP2, MMP9 expression and collagen remodeling in left ventricle of rabbit undergoing chronic pressure overload. Methods 30 rabbits were randomly divided into 3 groups (n= 10,each group), including sha