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呼吸暂停是指呼吸停止时间超过20s并伴有紫绀和心率减慢(<100次/min),多见于早产儿。早产儿原发性呼吸暂停(AOP)发生频率和严重程度与胎龄呈反比,过去认为AOP是呼吸中枢发育不成熟,引起呼吸调节障碍,近几年研究发现与血浆内啡肽类物质有关。我院应用纳洛酮治疗AOP40例,现报告如下。
Apnea refers to respiratory arrest more than 20s and accompanied by cyanosis and slow heart rate (<100 beats / min), more common in premature children. The frequency and severity of primary apnea (AOP) in premature infants is inversely proportional to gestational age. In the past, AOP was considered to be immature respiratory center and cause respiratory dysfunction. In recent years, it has been reported that plasma aporphine is related to plasma endorphins. Naloxone treatment of AOP40 cases in our hospital, are as follows.