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目的 探讨病毒性脑膜炎和病毒性脑炎 (即病脑 )患者脑脊液中一氧化氮 (NO)含量改变的临床意义。方法 应用相应试剂盒对 2 7例病脑患者和 15例非感染者 (对照组 )脑脊液中的NO进行测定。结果 病脑患者脑脊液中治疗前NO含量与治疗后及对照组比较明显增高 (P <0 .0 1)。结论 提示NO确实参与了病脑的病理过程 ,NO含量测定有助于病脑的诊断及了解病情变化。
Objective To investigate the clinical significance of cerebrospinal fluid nitric oxide (NO) in patients with viral meningitis and viral encephalitis. Methods The cerebrospinal fluid NO was measured in 27 patients with brain disease and 15 non-infected patients (control group) using the corresponding kit. Results Cerebrospinal fluid in patients with cerebrospinal fluid NO levels before treatment and after treatment and control group was significantly higher (P <0.01). Conclusions suggest that NO really involved in the pathological process of brain disease, NO content of the brain helps to determine the diagnosis and understanding of the disease changes.