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目的:探讨无症状脑梗死(SBI)患者认知功能障碍发病率及其影响因素。方法:随机选取78例SBI患者(DBI组)和78例性别、年龄及所伴有的慢性病相匹配的对照者(对照组)分别进行简易精神状态检查(MMSE)量表测验、画钟测验(CDT)、汉密尔顿抑郁(HAMD)量表检查,并对检测结果进行比较。分析SBI患者的年龄、病灶数、抑郁程度、血压,血糖及血脂对其认知功能的影响。结果:SBI认知功能障碍发生率(53.8%)明显高于对照组(33.3%),其MMSE、CDT评分明显低于对照组。结论:SBI患者出现认知功能障碍非常普遍,其认知功能下降与SBI患者年龄、脑梗死病灶数及是否伴有抑郁高血压、糖尿病及高血脂显著相关。
Objective: To investigate the incidence of cognitive dysfunction in asymptomatic cerebral infarction (SBI) and its influencing factors. Methods: A total of 78 SBI patients (DBI group) and 78 control subjects (control group) with gender, age and chronic diseases were randomly selected. The MMSE scale, CDT), Hamilton depression (HAMD) scale test, and the test results were compared. Analysis of SBI patients age, number of lesions, degree of depression, blood pressure, blood glucose and lipid on the cognitive function. Results: The incidence of cognitive impairment in SBI was significantly higher (53.8%) than that in control group (33.3%). MMSE and CDT scores were significantly lower in SBI group than in control group. CONCLUSIONS: The prevalence of cognitive impairment in SBI patients is very common. The decline of cognitive function is associated with the age of patients with SBI, the number of focal cerebral infarction, and whether or not they are associated with depression, diabetes and hyperlipidemia.