论文部分内容阅读
随着科技的发展和工业化生活程度的提高,变应性疾病愈来愈多,而其中最为重要的疾病之一的过敏性哮喘亦日益受到人们的关注和重视。变应原特异性免疫治疗法用于哮喘已有90余年,经典的常规免疫疗法及传统的皮下注射途径给药等措施存在自身的弊端。为了使得特异性免疫治疗更为有效、安全和便捷,相关学者专家在特异性免疫治疗给药方面做出了大量工作,从而出现了季节前免疫疗法、突击免疫疗法等非常规免疫,以及植入剂疗法、透皮疗法等新型全身给药途径,还有气管给药、口服给药、鼻黏膜吸入及舌下含服等局部给药途径的涌现。
With the development of science and technology and the improvement of industrialized living conditions, more and more allergic diseases are becoming more and more serious. Allergic asthma, one of the most important diseases, is also attracting more and more attention. Allergen-specific immunotherapy has been used in asthma for more than 90 years. The conventional immunotherapy and traditional subcutaneous injection methods have their own drawbacks. In order to make the specific immunotherapy more effective, safe and convenient, experts and scholars have done a lot of work on the specific immunotherapy, resulting in pre-season immunotherapy, immunization and other unconventional immunization, as well as implantation New systemic routes of administration, such as therapies and transdermal therapies, as well as the emergence of topical routes of administration such as tracheal administration, oral administration, inhalation of the nasal mucosa and sublingual administration.