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人体免疫缺陷病毒(HIV)是患AIDS 的原因,它仅能从病毒感染者T 细胞中的极少细胞检查出来,即末梢血T 细胞占10%,在整个细胞中占0.01%。以此可以说明HIV 为什么那么快地破坏T 细胞。众所周知,AIDS 在病毒感染者中极少发病,一般需有几年的潜伏期。因而,HIV 可能以无症状状态存在于血液之外。最近,专家们发现了HIV 存在于皮肤郎罕氏细胞内,此细胞起抗原提示作用,接收从皮肤侵入的抗原。在皮肤免疫方面,主要是提示皮肤浸润性辅助T细胞的抗原和其抗原相反应的T 细胞,同时受角质细胞所产生的中心白细胞素-1(TL-1)的激活,促使T
Human immunodeficiency virus (HIV) is the cause of AIDS. It can only be detected from very few T cells in virus-infected individuals, that is, 10% of peripheral blood T cells and 0.01% of whole cells. This can explain why HIV destroy T cells so quickly. It is well-known that AIDS is rare in those infected with the virus and generally requires a few years of incubation. Thus, HIV may exist asymptomatic outside of the bloodstream. Recently, experts found that HIV is present in the skin, Langerhans cells, which act as an antigen reminder to receive antigens invaded from the skin. In the aspect of skin immunity, it is mainly the T cells that prompt the skin-infiltrating helper T cells to react with their antigen, and the activation of central leukocyte-1 (TL-1) produced by keratinocytes at the same time causes T