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本文随机抽查北医大三院1994年10月出院病历345份,调查其中治疗心血管疾病药:β受体阻滞剂、钙拮抗剂、硝酸酯类、血管紧张素转化酶抑制剂(ACEI)、抗心律失常药等五类药的使用情况.采用WHO推荐的“限定日剂量(DDD)”的方法作为药物利用研究的测量单位,应用Ghodse教授建议的药物利用指数(DUI)为指标对病历进行分析.结果表明:①345份病历中109份使用治疗心血管疾病的5类药,约占31.65%.②使用的5类心血管药物有17个品种,出现频率最高的有硝酸异山梨酯(73例次)、硝苯地平(65例次)、硝酸甘油(41例次)、ACEI(29例次).③该5类心血管药物的使用与病人年龄相关.④15种药物的DUI均≤1.0,仅二种药稍>1.O提示无药物滥用情况,用药基本合理.
In this paper, we randomly selected 345 medical records of Bei Medical University Hospital from October 1994 to investigate the treatment of cardiovascular diseases such as beta blockers, calcium antagonists, nitrates, angiotensin converting enzyme inhibitors (ACEIs) Anti-arrhythmic drugs such as the use of five kinds of drugs.The WHO recommended “defined daily dose (DDD)” as a measure of drug use research units, the use of Professor Ghodse recommended drug use index (DUI) as an indicator of medical records The results showed that: (1) Of the 345 medical records, 109 used 5 kinds of drugs to treat cardiovascular diseases, accounting for 31.65% .② There were 17 varieties of 5 kinds of cardiovascular drugs used, the most frequent ones were isosorbide dinitrate (73 (N = 65), nitroglycerin (n = 41) and ACEI (n = 29) .③The use of these five cardiovascular drugs was related to patient’s age.④The DUI of all 15 drugs was ≤1.0 , Only two kinds of drugs slightly> 1.O prompt no drug abuse, medication is reasonable.