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1961年穆尔(Moore)首次报告南美洲出现恶性疟原虫对氯喹敏感性减低的现象。以后康塔科斯(Contacos)报告东南亚地区存在抗氯喹的恶性疟原虫。1973年我组发现云南省勐定地区恶性疟原虫对氯喹产生抗药性,随后进一步在德宏州昔马、畹町,西双版纳州勐棒等地进行调查,均证实有抗氯喹恶性疟原虫存在。现将调查资料整理如下。调查方法按世界卫生组织介绍的7日观察法进行。一、氯喹的剂量和用法选择病人为有疟疾临床症状、血检恶性疟原虫无性体阳性者。成人按标准氯喹量
1961 Moore (Moore) first reported in South America, Plasmodium falciparum decreased susceptibility to chloroquine phenomenon. Contacos later reported the presence of chloroquine-resistant Plasmodium falciparum in Southeast Asia. In 1973, we found that Plasmodium falciparum was resistant to chloroquine in Mengding area, Yunnan province. In 1973, we further investigated the resistance of Plasmodium falciparum to Plasmodium falciparum in Ximo, Wanding and Xishuangbanna in Dehong Prefecture. Survey information is now organized as follows. Survey method according to the World Health Organization on the 7th observation method. First, the dose and usage of chloroquine Select the patient for the clinical symptoms of malaria, blood tests of P. falciparum asexual positive. Adults according to the standard amount of chloroquine