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目的探讨儿童良性部分性癫痫（ＢＰＥ）的ＳＰＥＣＴ显像特点。方法２１例ＢＰＥ患儿，在ＥＥＧ监测下，分别在觉醒期（棘波发放间期）和睡眠期（棘波发放期）进行ＳＰＥＣＴ显像，减影处理后重建断层影像。用脑血流功能变化率（ＢＦＣＲ％）数学模型进行定量分析。结果ＥＥＧ监测显示患儿觉醒期背景活动基本正常，睡眠期棘波发放频率明显增多。ＳＰＥＣＴ共见１１７个痫灶，平均每例５６±１６个。ＳＰＥＣＴ显像特点为：①多灶性镜像分布；②主要位于Ｒｏｌａｎｄｉｃ区；③“环形征”；④觉醒期的多处放射性减低区，睡眠期放射性明显填充。ＳＰＥＣＴ与ＥＥＧ的符合率为９３１％（１０９／１１７）。痫灶的ＢＦＣＲ％皆高于对应正常局部脑自然变化的范围（９９％可信区间）。棘波发放频率和ＢＦＣＲ％之间无相关性（ｒ＝０４５，Ｐ＞００５）。结论ＢＰＥ痫灶异常放电时，可致局部脑血流灌注和功能异常
Objective To investigate the characteristics of SPECT imaging in children with benign partial epilepsy (BPE). Methods Twenty-one BPE children underwent SPECT imaging during the wake-up period (spike release period) and sleep period (spike release period) under the EEG monitoring, and the images were reconstructed after subtraction. Quantitative analysis was performed using the BFCR% mathematical model. Results EEG monitoring showed that the background activity of children during waking period was basically normal, and the frequency of spikes in sleep stage was significantly increased. There were 117 epileptic foci in SPECT, with an average of 5.66 ± 1.66 cases per case. SPECT imaging features are as follows: ① multifocal image distribution; ② mainly located in the Rolandic area; ③ “ring sign”; ④ awakening multiple radioactive areas, sleep significantly radioactive filling. The coincidence rate of SPECT and EEG was 931% (109/117). The BFCR% of the epileptogenic foci were both higher than the corresponding range of normal local brain changes (99% confidence interval). There was no correlation between spike wave frequency and BFCR% (r = 045, P> 005). Conclusion BPE epileptogenic abnormal discharge can cause regional cerebral perfusion and dysfunction