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HAV主要通过粪-口途径传播,弄清HAV在粪便中排出的持续时间对控制甲型肝炎是重要的。曾有人报道,甲型肝炎患者在出现症状后不久粪便的病毒排出即停止。虽然已有关于用PCR检出粪便中HAV的报道,但成人甲型肝炎患者粪便HAV排出的持续时间尚未被详尽描述过。本研究作者用RT-PCR法来检测成人甲型肝炎患者粪便中HAV RNA。
HAV is transmitted mainly through the fecal-oral route and it is important to understand the duration of HAV excretion in feces to control hepatitis A. It has been reported that hepatitis A patients stopped excretion of virus shortly after the onset of symptoms. Although detection of HAV in stool has been reported by PCR, the duration of excretion of fecal HAV in adult patients with hepatitis A has not been exhaustively described. The authors used RT-PCR to detect HAV RNA in feces of adult patients with hepatitis A.