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目的:观察外加稳恒直流电场对兔腹主动脉周围电势差的影响。方法:在兔腹主动脉两侧腰大肌埋置刺激电极,在血管外膜、血管内外膜间安置测量电极,给予稳恒直流电场刺激,电场强度采用3V或4V,记录电场刺激前后血管周围电势差的变化情况。结果:①通电后即刻,血管周围电势差与通电前相比无变化(P>0.05)。②通电后30min,血管外膜间和血管内外膜间电势差均明显增加,4V组增加更为明显。③断电后30min,两外膜间电势差基本恢复至通电前水平,而血管内外膜间电势差仍高于通电前,两刺激电极间仍有较高电势差存在。结论:将铂电极置入兔腰大肌,连接稳恒直流电源后构成的是一个RC电路,应用3V电压或者4V电压刺激都可以引起血管周围电势的变化。
Objective: To observe the effect of applied steady-state DC electric field on the potential difference around the abdominal aorta. Methods: Stimulation electrodes were embedded in the psoas muscle of the abdominal aorta on both sides of the rabbit. The measuring electrodes were placed between the adventitia and the intima and blood vessels of the rabbit aorta. The electrodes were stimulated by a steady DC electric field. The electric field intensity was 3V or 4V. Potential difference changes. Results: ① Immediately after electrification, there was no change in the potential difference between the perivascular and post-electroporation (P> 0.05). 30min after electroporation, the potential difference between the vascular adventitia and the vascular intima and endocardium significantly increased, the more obvious in 4V group. ③ After 30min, the potential difference between the two adventitial membranes recovered to the level before energization, but the potential difference between the inner and the outer membrane was still higher than that before energization. There was still a higher potential difference between the two stimulating electrodes. CONCLUSION: Placing platinum electrodes into the psoas muscle, connected to a steady DC power supply, constitutes an RC circuit. The application of 3V voltage or 4V voltage stimulation can cause changes in the potential around the blood vessels.