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Alzheimers disease is the ultimate scourge of mankind that hauntnts the ageing population and increasingly becomes the major health and social problem faced by our society.Alzheimers disease(AD),described by Alois Alzheimer[1] as dementia praecox (and named Alzheimers disease by Emil Kraepelin several years later[2]),is a severe neurodegenerative pathology associated with specific histopathological markers represented by focal extracellular deposits of fibrillar β-amyloid (also called neuritic or senile plaques) in the parenchyma of the brain and in the walls of blood vessels,and intraneuronal accumulation of neurofibrillary tangles that are composed of abnormal hyperphosphorylated tau filaments[3].