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目的评价河南省2016年麻疹实验室运转情况。方法通过中国麻疹监测信息管理系统和河南省麻疹网络实验室,收集和分析河南省2016年麻疹实验室监测数据。结果 2016年全省报告麻疹监测病例4 018例,采集血标本3 960例(98.56%),麻疹IgM抗体检测阳性率为26.72%(1 055/3 949)。采集健康人群血标本449例,麻疹IgG抗体检测阳性率为93.99%(422/449)。未发现麻疹暴发。采集监测病例的病原学标本3 522例(87.66%),麻疹病毒核酸检测阳性率为21.73%(720/3 313)。省级麻疹实验室接收省直管县送检的病例咽拭子129份,获得麻疹病毒分离株33份;接收7个市级实验室送检的麻疹病毒分离株24份。全部病毒分离株为中国本土流行的H1a基因亚型。省级麻疹实验室通过了世界卫生组织2016年职能考核;18家市级麻疹实验室及10家省直管县麻疹实验室全部通过省级麻疹实验室组织的职能考核。结论河南省省、市、县三级麻疹实验室网络运转良好,本土麻疹H1a基因型仍持续流行,未发现输入病例。
Objective To evaluate the operation of measles laboratory in Henan Province in 2016. Methods Through the China measles monitoring information management system and Henan measles network laboratory, collect and analyze the monitoring data of measles laboratory in Henan province in 2016. Results In 2016, 4 018 cases of measles surveillance were reported in the province, and 3 960 cases (98.56%) of blood samples were collected. The positive rate of measles IgM antibody detection was 26.72% (1 055/3 949). A total of 449 blood samples were collected from healthy subjects. The positive rate of measles IgG antibody was 93.99% (422/449). No measles outbreak found. A total of 3 522 etiological specimens (87.66%) were collected from surveillance surveillance. The positive rate of measles virus nucleic acid detection was 21.73% (720/3 313). The Provincial Measles Laboratory received 129 cases of throat swabs delivered by provincial straight-line counties, obtained 33 copies of measles virus isolates and received 24 copies of measles virus isolates from 7 municipal-level laboratories. All virus isolates are H1a subgenotypes popular in China. The provincial measles laboratory passed the functional examination of WHO in 2016; 18 municipal measles laboratories and 10 provincial straight-line measles laboratories all passed the functional examination organized by the provincial measles laboratory. Conclusion The network of measles laboratories at provincial, municipal and county level in Henan Province is working well. The H1a genotype of local measles still continues to prevail, and no imported cases were found.