Establishment of cell lines with porcine spermatogonial stem cell properties

• 作 者: Yi Zheng Tongying Feng Pengfei
• 机 构: KeyLaboratoryforAnimalGenetics
• 出 处: 畜牧与生物技术杂志:英文版
• 发表日期: 2020年3期
• 关键词: IMMORTALIZATION PIG SELF-RENEWAL Spermatogonial stem cells SV40 large T antigen
• 基金项目: This study was supported by the National Natural Science Foundation of China(Grant No.31572401,31772605)to W.Z.,the Open Fund of Farm Animal Genetic Resources Exploration and Innovation Key Laboratory

Background:Spermatogonial stem cells(SSCs)are capable of both self-renewal and differentiation to mature functional spermatozoa,being the only adult stem cells in the males that can transmit genetic information to the next generation.Porcine SSCs hold gre