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目的:研究米非司酮联合不同剂量米索前列醇在终止妊娠方面的临床效果。方法:随机选择终止妊娠的妇女80例并随机分为两组。两组均予以米非司酮口服,对照组仅采用阴道后穹隆置米索前列醇600μg;口服米索前列醇400μg,阴道后穹隆置入米索前列醇400μg。比较不同配伍剂量米索前列醇的终止妊娠效果、期间并发的不良反应。结果:观察组40例患者终止妊娠成功率为92.5%,相比对照组患者的72.5%有显著差异(P<0.05)。观察组患者不良反应的发生率明显低于对照组,差异具有统计学意义(P<0.05)。结论:米非司酮联合800μg米索前列醇口服、阴道后穹隆置药在临床终止妊娠方面的效果更加显著,提高终止妊娠效果。
Objective: To study the clinical effect of mifepristone combined with different doses of misoprostol in termination of pregnancy. Methods: Eighty randomly selected women who terminated pregnancy were randomly divided into two groups. Both groups were given mifepristone orally, the control group only with misoprostol vaginal posterior dome 600μg; oral misoprostol 400μg, vaginal posterior fornix 400ml misoprostol. Comparison of different compatibility dose misoprostol termination of pregnancy effect, concurrent adverse reactions. Results: The success rate of termination of pregnancy in 40 patients in observation group was 92.5%, which was significantly different from that in control group (72.5%, P <0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group, the difference was statistically significant (P <0.05). Conclusion: The effect of oral administration of mifepristone combined with 800 μg misoprostol on vaginal posterior fornix in clinical termination of pregnancy is more significant and the effect of termination of pregnancy is improved.