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已发现某些恶性肿瘤及良性非赘生性疾患病例血清铜水平升高。铜水平和恶性肿瘤生长活性之间的密切联系,通常见于恶件淋巴瘤。妇科恶件肿瘤中以往仅对宫颈及卵巢癌进行过血清铜水平调查。本研究目的为估价在各种妇科恶性肿瘤中,血清铜水平作为肿瘤标记的意义。作者选择在Hadassah大学医院妇科住院的179例疑患妇科恶性肿瘤的病人,进行连续4年的研究。肿瘤的临床分期按国际妇产科联盟(FIGO)标准,最终诊断依据组织学。患肝病、接受雌激素或其他激素治疗的病人除外。20例健康妇女做对照。标本经严格的收集、贮存、分离和冰冻处理,用原子吸收分光光度计测定。结果:179例中103例患妇科癌肿(外阴癌9例、
Some malignancies and benign non-neoplastic disorders have been found to have elevated levels of serum copper. The close association between copper levels and the growth activity of malignant tumors is commonly found in malignant lymphoma. Gynecological malignant tumors in the past only for cervical and ovarian cancer serum copper level survey. The aim of this study was to evaluate the significance of serum copper levels as a tumor marker in various gynecologic malignancies. The authors selected 179 patients with suspected gynecological malignancies hospitalized in the gynecology department of Hadassah University Hospital for 4 consecutive years. The clinical stage of the tumor is based on the FIGO standard and the final diagnosis is based on histology. Liver disease, except for those receiving estrogen or other hormonal therapies. 20 healthy women as a control. Specimens were collected, stored, separated, and frozen in a rigorous fashion using atomic absorption spectrophotometry. Results: Of 179 cases, 103 cases had gynecological cancer (9 cases of vulvar cancer,