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口服乙胺丁醇引起颗粒细胞减少,尚未见到报导,今就我院应用乙胺丁醇引起颗粒细胞减少二例,报告如下: 病例Ⅰ,男性,42岁,患肺结核曾用INH、RFP、EB治疗,1981年4月15日入本院后继用INH、RFP、SM。血常规发现WBC3,200,N42％,L52％,M1％。十天后复查WBC,3,100,当时考虑粒细胞减少与RFP有关,故停用RFP改用EB1.0/日,一个月后复查WBC_2,700,N46％,L54％。立即给予维生素B_4及利血生等药,WBC波动在3,100～2,300之间达二月之久,为明确粒细胞减少的原因,停用一切抗结核药物。两周后WBC4,100。先后试用SM,INH,二周后WBC6,500,继而给予EB1.0g/日,二周后WBC3,400,为避免偶然性,又停用EB二周,WBC升至6,400,再试EB
Ethambutol oral granulosa cells caused by decreased, has not yet been reported, now our hospital ethambutol caused by granulocytopenia in two cases, the report is as follows: Case I, male, 42 years old suffering from tuberculosis INH, RFP, EB treatment, April 15, 1981 into the hospital followed by INH, RFP, SM. Blood found WBC3,200, N42%, L52%, M1%. Ten days later review of WBC, 3,100, was considered the occasion of neutropenia and RFP, so disable the use of RFP to EB1.0 / day, one month after the review WBC_2,700, N46%, L54%. Immediately given vitamin B_4 and reserpine and other drugs, WBC fluctuations between 3,100 ~ 2,300 up to February, in order to clarify the cause of neutropenia, disable all anti-TB drugs. Two weeks after WBC4,100. SM, INH were tested two weeks later, WBC6,500, followed by EB1.0g / day, WBC3,400 two weeks later, to avoid chance, but also disabled EB two weeks, WBC rose to 6,400, and then try EB