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为缓解胆道梗阻,对28例恶性胆道梗阻(MBO)患者行经内镜胆管内引流术(EBD)。结果25例(89%)插管成功,共插管44次,7F管3次,10F25次,12F16次。23例(92%)减黄有效,EBD后第3天胆红素平均下降46.3%,肝外胆管径平均回缩58.6%,减黄有效者腹胀迅速消失或减轻。首次插管维持有效引流时间141.5±151.2天,早、中期并发胆管炎40%,1年以上生存17%。结果表明EBD减黄效果和症状改善是显著的,胆红素下降与胆管径回缩相平行。认为胆管是否屈曲及乳头括约肌切开术的好坏是EBD成败的关键;腹胀再现,有胆道感染症状及B超见肝外胆管扩张为通管的指征。EBD适合高龄或高危人群的MBO患者,对延长生存期有重要的价值。
To relieve biliary obstruction, endoscopic biliary drainage (EBD) was performed in 28 patients with malignant biliary obstruction (MBO). Results Twenty-five patients (89%) were successfully intubated, with a total of 44 intubations, 7F tubes 3 times, 10F 25 and 12F 16. 23 cases (92%) were effective in reducing yellowing. After the first 3 days of EBD, bilirubin decreased by an average of 46.3%, and the extrahepatic bile duct diameter retracted by 58.6%. The diarrhea in the effective yellow reducing group quickly disappeared or decreased. The first intubation maintained an effective drainage time of 141.5±151.2 days. In the early and mid-term, 40% of cholangitis was complicated and 17% of patients survived for more than 1 year. The results showed that the yellowing effect and symptoms of EBD were significantly improved. The decrease of bilirubin was parallel to the retraction of biliary diameter. Whether the bile duct is flexed or whether the sphincterotomy is good or not is the key to the success or failure of EBD; bloating reappears, there are symptoms of biliary tract infections, and B-scan sees the indication of extrahepatic bile duct dilation as a guide. EBD is suitable for MBO patients with advanced age or high risk. It is of great value for prolonging survival.