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某些组织学类型的乳腺良性病变增加乳腺癌的风险。乳腺良性病变组织学上分为非增生性病变、增生性病变伴或不伴有非典型增生型。伴有异型增生的增生型病变有很高的恶变风险,其次是不伴有非典型增生的增生型病变。一般来讲,非增生性病变而且无乳腺癌家族史与普通人群一样并不增加乳腺癌风险;然而,一些复杂组织学类型,如不伴有异型增生的硬化性腺病、放射性瘢痕及乳头状瘤是否增加恶变风险尚不明确。
Some histological types of benign breast lesions increase the risk of breast cancer. Breast benign lesions histologically divided into non-proliferative lesions, proliferative lesions with or without atypical hyperplasia. Hyperplastic lesions associated with dysplasia have a high risk of malignancy, followed by hyperplastic lesions not associated with atypical hyperplasia. In general, non-proliferative lesions and absence of a family history of breast cancer do not increase the risk of breast cancer, as is the general population; however, some complex histological types, such as sclerosing adenosis not associated with dysplasia, radioactive scars and papilloma Whether to increase the risk of malignant transformation is not yet clear.