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目的观察纳米碳混悬液与美蓝在乳腺癌前哨淋巴结活检中的应用。方法选择2013年1月至2015年12月至我院诊断为乳腺癌并进行SLNB的患者86例,按照来诊时间排序,序列号为单号患者作为纳米碳组,序列号为双号患者作为美蓝组,各43例,分别使用纳米碳混悬液与美蓝作为示踪剂行乳腺癌前哨淋巴结活检,观察两组患者SLN检出情况以及发生示踪不理想的情况比例。结果纳米碳组患者SLN检出率明显高于美蓝组,而示踪不理想发生情况明显低于美蓝组,且具有统计学差异(P<0.05)。纳米碳组患者无改行腋淋巴清扫术患者,而美蓝组患者有2例改行腋淋巴清扫术。结论使用纳米碳混悬液作为示踪剂进行乳腺癌前哨淋巴结活检,其临床效果优于使用美蓝作为示踪剂。
Objective To observe the application of nanocarbon suspension and methylene blue in sentinel lymph node biopsy of breast cancer. Methods From January 2013 to December 2015, 86 cases diagnosed with breast cancer and SLNB in our hospital were selected. According to the timing of consultation, the patients with single serial number were treated as carbon nano group and the patients with double serial number as double Methylene blue group and 43 cases in each group. Sentinel lymph node biopsy of breast cancer was performed using nano-carbon suspension and methylene blue as tracer respectively. The detection rate of SLN and the proportion of cases where tracer was not ideal were observed. Results The detection rate of SLN in patients with carbon nano was significantly higher than that in methylene blue group, while the incidence of tracer suboptimal was significantly lower than that in methylene blue group (P <0.05). There were no patients with axillary lymph node dissection in the patients with carbon nanocarbons, and axillary lymph node dissection in 2 patients with methylene blue. Conclusions Sentinel lymph node biopsy of breast cancer using nanocarbon suspension as a tracer is superior to methylene blue as a tracer.