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氨基酸是构成蛋白质的结构单元 ,尿素是较强的蛋白质变性剂 .因此 ,研究水溶液中氨基酸与尿素的相互作用对于探索蛋白质变性的分子机理、预测蛋白质的变性规律具有重要的意义 .在前期工作中 ,我们研究了 α-氨基酸在尿素 [1] 和乙酸钠[2 ] 水溶液中的体积性质 .作为水溶液中氨
Amino acids are the building blocks of proteins and urea is a strong protein denaturant.Therefore, to study the interaction between amino acids and urea in aqueous solution is of great significance in exploring the molecular mechanism of protein denaturation and predicting the denaturation of proteins.In the previous work , We investigated the volumetric properties of a-amino acids in aqueous urea [1] and sodium acetate [2] solutions as aqueous ammonia