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研究表明，肿瘤的耐药与多药耐药基因mdrl的扩增和／或其编码的P170的过度表达有关[1]。本研究应用SP免疫组比法，检测P170在不同组织类型、不同分化程度肺癌组织中的表达，现将结果报告如下。1材料与方法1．1材料本组病人48例，其中非小细胞肺癌（NSCLC）42例（鳞癌19例，腺癌
Studies have shown that tumor resistance is associated with the amplification of multidrug resistance gene mdrl and/or its overexpression of encoded P170 [1]. In this study, SP immunohistochemistry was used to detect the expression of P170 in lung cancer tissues of different tissue types and different degrees of differentiation. The results are reported below. 1 Materials and methods 1.1 Materials 48 patients in this group, including 42 cases of non-small cell lung cancer (NSCLC) (19 cases of squamous cell carcinoma, adenocarcinoma