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目的 :分析研究前列地尔对早期糖尿病肾病的治疗效果。方法 :选取2014年3月—2016年3月我院收治的60例早期糖尿病肾病患者作为本次研究的研究对象,随机将患者分为对照组和观察组,每组各30例患者。两组患者均给予常规基础治疗,对照组患者加用替米沙坦治疗,观察组患加用前列地尔治疗,对比分析两组患者的临床治疗效果。结果 :两组患者治疗后观察组患者的24h尿蛋白、平均动脉压下降幅度大于对照组,P<0.05,两组比较差异有统计学意义。血肌酐、血尿素氮、空腹血糖值变化不明显,P>0.05。结论 :前列地尔对早期糖尿病肾病具有很好的临床治疗效果。
Objective: To analyze the therapeutic effect of alprostadil on early diabetic nephropathy. Methods: From March 2014 to March 2016, 60 patients with early diabetic nephropathy admitted to our hospital were selected as the study subjects. The patients were randomly divided into control group and observation group, with 30 patients in each group. Two groups of patients were given routine basic treatment, the control group plus telmisartan treatment, observation group plus alprostadil treatment, comparative analysis of two groups of patients with clinical treatment. Results: After 24 hours of treatment, the urinary protein and mean arterial pressure of observation group decreased significantly in both groups (P <0.05). There was significant difference between the two groups. Serum creatinine, blood urea nitrogen, fasting blood glucose values did not change significantly, P> 0.05. Conclusion: Alprostadil has good clinical therapeutic effect on early diabetic nephropathy.