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目的:观察病理性黄疸新生儿红细胞葡萄糖-6-磷酸脱氢酶(G6PD)缺陷合并弓形体(TOX)感染的关系。方法:采用聚合酶链反应(PCR)技术对179例被确诊为病理性黄疸新生儿患者进行血清TOX检测,并同时进行G6PD、血常规、胆红素等各项指标的测定,进行比较。结果:179例病理性黄疸新生儿中,TOX 41例(22.90%),G6PD缺陷者24例(13.41%),G6PD缺陷+TOX感染者18例(10.06%)。结论:G6PD缺陷合并TOX感染之间存在显著性相关。
Objective: To observe the relationship between erythrocyte glucose 6-phosphate dehydrogenase (G6PD) deficiency and toxoplasma (TOX) infection in neonates with pathological jaundice. Methods: Serum TOX was detected in 179 newly diagnosed patients with pathological jaundice by polymerase chain reaction (PCR) technique. At the same time, G6PD, blood routine, bilirubin and other indicators were measured and compared. Results: Of the 179 cases with pathological jaundice, 41 (22.90%) had TOX, 24 (13.41%) had G6PD deficiency, and 18 (10.06%) had G6PD deficiency + TOX infection. Conclusion: There is a significant correlation between G6PD deficiency and TOX infection.