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目的：分析６２例经临床、实验室检查及病理证实的垂体巨腺瘤的ＭＲＩ表现及与激素水平的关系。材料和方法：根据肿瘤大小将垂体巨腺瘤分成三组：１、１．０～２．０ｃｍ（８例）；２、２．１～３．０ｃｍ组（１５例）；３、〉３．０ｃｍ组（３９例）。根据临床表现及血清激素水平又将垂体巨腺瘤分成泌乳素组（ＰＲＬ，３４例），生长激素组（ＧＨ，１８例），非激素分泌组（ＮＨＳ，１０例）。结果：第三组中出现鞍隔切迹腰征、鞍上池闭塞、视交叉受压、海绵窦受侵、颈内动脉推移或包裹、蝶鞍扩大以及肿瘤突入蝶窦等表现明显高于前两组，且有统计学意义。ＰＲＬ组较易发生囊变、海绵窦受侵、颈内动脉推移或包裹、蝶鞍扩大以及肿瘤突入蝶窦等表现，且有统计学意义。ＧＨ组较易出现腰征、鞍上池闭塞、视交叉受压和第三脑室受压等表现。结论：提出对于ＰＲＬ腺瘤应重点观察蝶鞍、鞍底和鞍旁是否受侵，ＧＨ腺瘤应重点观察鞍上区是否受侵。ＭＲＩ检查有助于垂体巨腺瘤的定性诊断。
Objective: To analyze the MRI features of 62 cases of pituitary macroadenomas confirmed by clinical, laboratory examinations and pathology and their relationship with hormone levels. Materials and Methods: Pituitary giant adenomas were divided into three groups according to the size of the tumor: 1, 1.0-2.0 cm (8 cases); 2, 2.1-3.0 cm group (15 cases); 3, 〉3. 0cm group (39 cases). According to clinical manifestations and serum hormone levels, pituitary macroadenomas were divided into prolactin group (PRL, 34 cases), growth hormone group (GH, 18 cases), and non-hormonal secretion group (NHS, 10 cases). RESULTS: In the third group, saddle septal waist syndrome, suprasellar cistern occlusion, optic chiasm compression, cavernous sinus invasion, internal carotid artery passage or enveloping, sella enlargement, and tumor invagination into sphenoid sinus were significantly higher than those in the former group. Two groups, with statistical significance. In the PRL group, cystic changes, invasion of the cavernous sinus, migration or enveloping of the internal carotid artery, enlargement of the sella, and invasion of the tumor into the sphenoid sinus were more likely to occur, and there was statistical significance. The GH group was more prone to lumbar sign, suprasellar cistern occlusion, optic chiasmatic pressure, and third ventricle compression. Conclusion: It is proposed that whether PRS adenoma should be focused on whether the sella, saddle and saddle are invaded. GH adenoma should focus on whether the suprasellar region is invaded. MRI examination is helpful for the qualitative diagnosis of pituitary giant adenomas.