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哺乳动物蛋白经内质网膜离开细胞进入分泌途径,此蛋白在N末端包含一个被称为信号序列的特异的核心疏水肽基团。蛋白通过内质网膜转动是共翻译且分泌的信号序列,Ⅰ型跨膜蛋白通常由一种信号肽酶加工。一种非断裂的信号序列,可能是从N-末端凹陷,允许其他拓扑形式的跨膜蛋白进入内质网膜,锚定膜蛋白。编码分泌蛋白的寄生虫
Mammalian proteins leave the cell via the endoplasmic reticulum membrane and enter the secretory pathway, which contains a specific core hydrophobic peptide group at the N-terminus called the signal sequence. Protein is transported through the endoplasmic reticulum and is a co-translated and secreted signal sequence. Type I transmembrane proteins are usually processed by a signal peptidase. A non-fragmented signal sequence may be recessed from the N-terminus, allowing other topical transmembrane proteins to enter the ER membrane and anchor the membrane protein. Parasites encoding secretory proteins