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为观察煤矽肺患者血脂及脂质过氧化物(Lpo)含量,选择156例0—Ⅰ、Ⅰ、Ⅱ和Ⅲ期病例为对象,34例健康工人作对照,同时测定44例治疗与非治疗的患者血磷脂。结果发现0—Ⅰ及各期煤矽肺病人总脂、甘油三酯和胆固醇无显著改变;磷脂和 Lpo 含量增加;治疗组血磷脂下降;治疗前后有明显差别。据此认为:血磷脂似可作为煤矽肺的辅助诊断和判断疗效的观察指标,Lpo 对煤矽肺发病有重要意义。
To observe the blood lipid and lipid peroxidation (Lpo) in patients with coal silicosis, 156 patients with stage 0-Ⅰ, Ⅰ, Ⅱ and Ⅲ were selected as subjects and 34 healthy workers as control. At the same time, 44 patients with and without treatment Patients with phospholipids. The results showed that there was no significant change of total fat, triglyceride and cholesterol in patients with 0-Ⅰ and various stages of coal silicosis, phospholipid and Lpo content increased, and serum phosphatide decreased in the treatment group. There was a significant difference before and after treatment. Accordingly, it is considered that the phospholipids can be regarded as an auxiliary index to diagnose and judge the effect of coal silicosis, and Lpo is of great significance to the pathogenesis of coal silicosis.