Comparison of gene expression in cynomolgus monkeys with preclinical type II diabetes induced by dif

• 作 者: Li-Sha Jin Jun-Hua Rao Li-Biao
• 机 构: GuangdongKeyLaboratoryofAnimalConservationandResourceUtilization,SouthChinaBotanicalGarden
• 出 处: 动物模型与实验医学(英文)
• 发表日期: 2019年1期
• 关键词: CYNOMOLGUS MONKEY gene expression high energy DIET PRECLINICAL phase type 2 diab
• 基金项目: Science and Technology Planning Project of Guangdong Province,Grant/Award Number:2016A030303037 and 2017A070702014,Natural Science Foundation of Guangdong Province,(2018A030313307),National Natural Sc

Background:C ynomolgus disease models that are similar to the preclinical stage of human type 2 diabetes mellitus(T2 DM)were established by feeding middle-aged cynomolgus monkeys different high energy diets to study the differential expression of diabetes