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作者用光镜和电镜对两例肝豆状核变性的肝穿刺标本进行了细胞和亚细胞的组织病理学观察;并运用电子探针对铜在细胞内的分布进行了初步分析。结果提示:铜在细胞内的分布形式与细胞的病变密切相关;溶酶体在本病的发生和发展过程中可能占有的重要地位。
The authors used light microscopy and electron microscopy of hepatolenticular degeneration of liver hepatolenticular specimens of two cases of cells and subcellular histopathological observations; and the use of electron probe for the distribution of copper in the cells were analyzed. The results suggest that the distribution of copper in the cell is closely related to the cell pathological changes. The lysosome may occupy an important position in the occurrence and development of this disease.