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目的观察生长抑素治疗急性重症胰腺炎的临床效果。方法选择急性重症胰腺炎患者76例为研究对象,根据入院先后顺序分为2组,各38例。对照组患者采用常规治疗,观察组患者在常规治疗的基础上采用生长抑素治疗,对比观察2组临床治疗效果。结果观察组总有效率100.00%,高于对照组89.41%(P<0.05)。观察组治愈时间为(4.2±1.3)d,短于对照组的(8.4±2.2)d(P<0.01);观察组血淀粉酶恢复时间为(6.2±0.8)d,短于对照组的(12.3±3.4)d(P<0.01);观察组并发症发生率为7.89%,低于对照组的26.32%(P<0.05)。结论采用生长抑素治疗急性重症胰腺炎,可有效改善患者的临床症状与体征,减少并发症发生率,促进患者康复。
Objective To observe the clinical effect of somatostatin on acute severe pancreatitis. Methods A total of 76 patients with severe acute pancreatitis were selected as study subjects and divided into 2 groups according to the sequence of hospital admission: 38 cases each. The patients in the control group were treated with conventional therapy. The patients in the observation group were treated with somatostatin on the basis of routine treatment. The clinical effects of the two groups were compared. Results The total effective rate was 100.00% in the observation group, which was 89.41% higher than that in the control group (P <0.05). The healing time in the observation group was (4.2 ± 1.3) days, shorter than that in the control group (8.4 ± 2.2 days) (P <0.01). The amylase recovery time in the observation group was (6.2 ± 0.8) days, shorter than that in the control group 12.3 ± 3.4) d (P <0.01). The incidence of complications in the observation group was 7.89%, which was lower than that in the control group (26.32%, P <0.05). Conclusion The use of somatostatin in the treatment of acute severe pancreatitis can effectively improve the clinical symptoms and signs of patients, reduce the incidence of complications and promote patient rehabilitation.