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目的分析2型糖尿病(T2DM)患者血中糖化血红蛋白(Hb A1c)检测的临床意义。方法采用离子交换高效液相色谱法(HPLC)对T2DM患者1 015例与非T2DM的健康人280例全血Hb A1c进行检测并进行比较。结果 T2DM患者Hb A1c值明显高于对照组,差异有统计学意义(P<0.01)。结论 Hb A1c的检测对了解T2DM患者的血糖控制状况及预防慢性并发症有重要意义。
Objective To analyze the clinical significance of detecting hemoglobin A1c (Hb A1c) in type 2 diabetes mellitus (T2DM). Methods The serum levels of Hb A1c in whole blood of 1 015 cases of T2DM patients and 280 healthy people without T2DM were detected by ion exchange high performance liquid chromatography (HPLC). Results The Hb A1c in patients with T2DM was significantly higher than that in the control group (P <0.01). Conclusion The detection of Hb A1c is of great significance in understanding the glycemic control and preventing chronic complications in patients with T2DM.