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目的了解南阳某专科学校入学新生乙肝病毒的感染情况,为乙肝的防治提供依据。方法用ELISA方法对该校2002年和2007年秋季入学新生乙肝病毒血清标志物(两对半)进行检测和用改良赖氏法对肝功能进行检测。结果2002年被检新生2 400人,HBsAg阳性者126人(占5.25%),其中男生78人,阳性率为8.90%,女生48人,阳性率为3.15%;农村学生HBsAg阳性率为5.90%,城镇学生阳性率为0.95%;表抗体(抗-HBs)阳性率为23.58%;ALT阳性率为2.63%。2007年被检新生4 655人,HBsAg阳性者133人(占2.86%),其中男生45人,阳性率为3.07%,女性88人,阳性率为2.76%;农村学生HBsAg阳性率为3.18%,城镇学生阳性率为1.10%;抗-HBs阳性率为48.18%;ALT阳性率1.12%。结论2007年入学新生HBsAg阳性率明显低于2002年入学新生,而抗-HBs阳性率明显高于2002年入学新生。严格入学新生乙肝病毒血清标志物和肝功能的检测,及时治疗病人和对乙肝表抗阴性者接种乙肝疫苗,对有效地保护易感人群,确保学生的健康具有十分重要的意义。
Objective To understand the status of hepatitis B virus infection among freshmen in a college in Nanyang and to provide evidence for the prevention and treatment of hepatitis B virus. Methods The serological markers of hepatitis B virus (two pairs and a half) of freshmen admitted to the school in autumn of 2002 and 2007 were detected by ELISA and the liver function was tested by modified Lysozyme. Results In 2002, 2 400 newborns were detected, of whom 126 were HBsAg positive (5.25%), of which 78 were male, with a positive rate of 8.90% and a female rate of 3.15%. The positive rate of HBsAg in rural students was 5.90% , The positive rate of urban students was 0.95%; the positive rate of anti-HBs was 23.58%; the positive rate of ALT was 2.63%. There were 4 655 newly diagnosed HBsAg positive persons (accounting for 2.86%) in 2007, of which 45 were male, the positive rate was 3.07% and the female rate was 2.76%. The positive rate of HBsAg in rural students was 3.18% The positive rate of urban students was 1.10%; the positive rate of anti-HBs was 48.18%; the positive rate of ALT was 1.12%. Conclusions The positive rate of HBsAg in freshmen in 2007 was significantly lower than that of freshmen in 2002, while the positive rate of anti-HBs was significantly higher than that of freshmen in 2002. Strictly admitted newborn hepatitis B virus serum markers and liver function testing, timely treatment of patients and anti-hepatitis B hepatitis B vaccination against hepatitis B vaccine, to effectively protect the susceptible population and ensure the health of students is of great significance.