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目的99mTc-N-NOET心肌灌注显像(MPI)对可疑或确诊冠心病(CAD)患者的预后评估价值。方法111例患者行99mTc-N-NOET运动和延迟门控MPI(GMPI),随后随访是否发生心脏事件(CE)。结果平均随访(33.47±7.69)个月,10例发生CE,单因素和多因素逐步Logistic回归分析结果显示,预测CE发生最有价值的危险因素包括异常心肌显像(χ2=8.69,P<0.05)和运动心肺比值(HLRex)(χ2=4.107,P<0.05),其中最重要的是HLRex。当HLRex<1.5时CE发生的危险性明显升高(相对危险度9.505,P<0.05)。结论99mTc-N-NOET MPI可作为预测可疑或确诊CAD患者发生CE的无创性检查方法;根据HLRex的大小可有效区分高危和低危患者。
Objective To evaluate the prognostic value of 99mTc-N-NOET myocardial perfusion imaging (MPI) in patients with suspected or confirmed coronary heart disease (CAD). Methods 111 cases of 99mTc-N-NOET exercise and delayed gating MPI (GMPI) were followed up for cardiac events (CE). Results The average follow-up (33.47 ± 7.69) months, 10 cases of CE, single factor and multivariate stepwise Logistic regression analysis showed that predicting the most valuable risk factors for CE include abnormal myocardial imaging (χ2 = 8.69, P <0.05 ) And heart rate (HLRex) (χ2 = 4.107, P <0.05), of which the most significant was HLRex. When HLRex <1.5, the risk of CE was significantly increased (relative risk 9.505, P <0.05). Conclusion The 99mTc-N-NOET MPI can be used as a noninvasive method to predict the occurrence of CE in patients with suspected or confirmed CAD. According to the size of HLRex, the high and low risk patients can be effectively distinguished.