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目的:探讨叶酸联合人绒毛膜促性腺激素(human chorionic gonodotropin,HCG)对习惯性流产妇女叶酸水平的影响。方法:80例习惯性流产妇女随机分为对照组(叶酸)和观察组(叶酸联合HCG),比较两组治疗前后血清叶酸水平及妊娠成功率。结果:观察组治疗后血清叶酸水平较对照组明显升高,P<0.05;观察组治疗后妊娠成功率较对照组明显提高,P<0.05。结论:叶酸联合HCG治疗习惯性流产能够显著升高血清叶酸水平,改善妊娠结局。
Objective: To investigate the effect of folic acid combined with human chorionic gonodotropin (HCG) on folic acid levels in habitual abortion women. Methods: Eighty women with habitual abortion were randomly divided into control group (folic acid) and observation group (folic acid combined with HCG). Serum folic acid levels and pregnancy success rate were compared between the two groups before and after treatment. Results: The level of serum folate in observation group was significantly higher than that in control group (P <0.05). The success rate of pregnancy in observation group was significantly higher than that in control group (P <0.05). Conclusion: Folic acid combined with HCG treatment of habitual abortion can significantly increase serum folic acid levels and improve pregnancy outcome.