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目的探讨系统性红斑狼疮（ＳＬＥ）消化系统累及的发生率及临床表现。方法对１９９０年１月～１９９７年７月北京协和医院诊断明确资料完整的２７７例ＳＬＥ住院病例进行分析。结果其中有消化系统症状体征或实验室异常者多达１５７例，占５６．７％。９８例（３５．４％）无明确酒精、药物、感染病因，且与ＳＬＥ活动性有关（Ｐ＜０．０１）。值得注意的是：４４例以胃肠病变为首发或主要表现的ＳＬＥ病例中，误诊３９例（８８．６％），最易误诊为感染性疾病，尤其是结核，其次为其它自身免疫性疾病及肿瘤。结论ＳＬＥ消化系统表现的发生率高，容易误诊，临床应引起重视。
Objective To investigate the incidence and clinical manifestation of digestive system in systemic lupus erythematosus (SLE). Methods From January 1990 to July 1997, Beijing Union Medical College Hospital diagnosed with complete information on 277 cases of SLE inpatients were analyzed. Results Among them, there were 157 cases of digestive system symptoms or laboratory abnormalities, accounting for 56.7%. Ninety-eight patients (35.4%) had no definite alcohol, drug and infectious etiology, and were related to SLE activity (P <0.01). It is noteworthy that among the 44 cases of SLE with gastrointestinal lesions as the first or main manifestation, 39 cases (88.6%) were misdiagnosed, most likely to be misdiagnosed as infectious diseases, especially tuberculosis, followed by other autoimmune diseases And cancer. Conclusions The incidence of SLE digestive system is high, it is easy to misdiagnosis, and clinical should pay attention to it.