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地高辛是临床上常用的口服强心苷类药物,其治疗窗窄,治疗剂量与中毒剂量接近,若使用时剂量把握不当或误服,则易致中毒[1]。我院最近收治了2例因误服大剂量地高辛而急性中毒的儿童,均出现严重的胃肠道、神经系统、心脏等方面的毒性反应,现报告如下。1病例资料病例1:患儿,女,4岁,体重15 kg,因“误服大剂量地高辛9+h伴频繁呕吐10+次”由外院急诊转入我院。患儿于入院前9+h与其弟一起玩耍(无大人照看),6h后即出现
Digoxin is commonly used in clinical oral cardiac glycosides drugs, the therapeutic window narrow, close to the dose and poisoning dose, if used properly dose or misdose, it is easy to cause poisoning [1]. Recently, 2 cases of acute poisoning caused by high dose of digoxin were accidentally taken in our hospital. All of them showed serious gastrointestinal, nervous system and cardiac toxic reactions. The report is as follows. 1 Case data Case 1: children, 4 years old, weighing 15 kg, because “inadvertently high-dose digoxin 9 + h with frequent vomiting 10 + times” from the hospital emergency department transferred to our hospital. Children with their younger brother played with 9 + h before admission (no adult care) and appeared after 6h