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最近全基因组相关性研究表明,15个独立的基因变体可能提示前列腺癌风险。但是,这些基因与前列腺癌的临床病理学特征之间的联系目前尚不清楚。作者系统分析了1 563例行前列腺根治性切除的前列腺癌患者肿瘤标本中的这15种基因变体。对所有患者采用相同的TNM肿瘤分期及Gleason评分
Recent genome-wide correlation studies have shown that 15 independent genetic variants may suggest a risk of prostate cancer. However, the link between these genes and the clinicopathological features of prostate cancer is unclear. The authors systematically analyzed these 15 gene variants in a total of 1 563 prostate cancer patients undergoing radical prostatectomy. The same TNM tumor staging and Gleason score were used for all patients