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各种溴代的烷基酚酮的乙酸酯用乙酸酐/三氟乙酸酐/乙酸(以下简称ATA)醋解可得高收率的相应的多乙酰氧基烷基酮,后者经稀酸水解几乎定量地得多羟基烷基酮。部分多乙酰氧基酮对肺癌A_(549)和上皮细胞癌显出抑制活性。
Acetic esters of various brominated alkyl ketones can be acetated with acetic anhydride / trifluoroacetic anhydride / acetic acid (hereinafter referred to as ATA) to give the corresponding polyacetoxyalkyl ketals in high yields, the latter By dilute acid hydrolysis almost quantitative polyhydroxyalkane ketone. Some PAHs showed inhibitory activity against lung cancer A 549 and epithelial cell carcinoma.