The role of Eph receptors in lens function and disease

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：a5354796

【摘要】

：

Cataract is the single largest contributor to blindness in the world,with the disease having a strong genetic component.In recent years the Eph family of recept

【作者】

：

SON Alexander I. PARK Jeong Eu

【机构】

：

DepartmentofChemicalBiology

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2012年5期

【关键词】

：

受体酪氨酸激酶镜头疾病遗传成分白内障盲目性生物学家族 cataract lens EphA2 ephrin-A5

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Cataract is the single largest contributor to blindness in the world,with the disease having a strong genetic component.In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens clarity.In this review we di

其他文献

A full-length 3D structure for MAPK/ERK kinase 2 （MEK2）

As a pivotal signal pathway,the Ras/Raf/MEK/ERK cascade can be activated by multiple extracellular stimuli and can transmit signals to diverse substrates.It rem

期刊

蛋白激酶三维结构ERK分子动力学模拟信号通路信号传递同源建模仿真结果MEK2 homology modeling molecular dyn

Screening for differentially expressed genes in Anoectochilus roxburghii （Orchidaceae） during symbio

Mycorrhizal fungi promote the growth and development of plants, including medicinal plants. The mechanisms by which this growth promotion occurs are of theoreti

期刊

差异表达基因菌根真菌金线莲共生期逆转录聚合酶链反应SPDDRT-PCRNorthernAnoectochilus roxburghii orc

Non-coding RNAs mediate the rearrangements of genomic DNA in ciliates

Most eukaryotes employ a variety of mechanisms to defend the integrity of their genome by recognizing and silencing parasitic mobile nucleic acids.However,recen

期刊

基因组DNA非编码RNA基因组重排RNA介导纤毛虫蛋白相互作用核糖核酸RNA干扰RNAi gene silencing scnRNA pi

Erratum to： Critical role of bioinformatics in translating huge amounts of next-generation sequencin

<正>~~

期刊

生物信息学数据转换个性化医学测序勘误美国食品管理局

Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its

Huntington's disease(HD) is caused by abnormal CAG repeat expansion in the 5′-end of the Huntingtin(HTT) gene.In addition to the canonical C-terminal full-

期刊

亚细胞定位聚集效应细胞质序列冠状动脉造影免疫印迹分析免疫细胞化学HTThuntingtin aggregates cytoplasmic l

Quantitative assessment of acute kidney injury by noninvasive arterial spin labeling perfusion MRI

The kidneys are essential for maintaining homeostasis,are responsible for the reabsorption of water,glucose and amino acids,and filter the blood by removing was

期刊

定量评估自旋标记肾损伤灌注动脉急性磁共振成像早期诊断arterial spin labeling （ASL） acute kidney inj

Translational medicine in China： Awareness is increasing and research is advancing

<正>Translational medicine, which was first described by the director of the National Institutes of Health in 2003, has received worldwide attention. It is now

期刊

中国医学转化美国国立卫生研究院临床实践基础科学以人为本科学家

Identification of a combination of SNPs associated with Graves＇ disease using swarm intelligence

Graves' disease,the production of thyroid-stimulating hormone receptor-stimulating antibodies leading to hyperthyroidism,is one of the most common forms of

期刊

单核苷酸多态性群体智能组合使用自身免疫性疾病粒子群优化算法甲状腺功能DNA变异SNPSGraves＇ diseasesingle nucleo

Magnetic resonance ultrashort echo time spin-echo imaging of the deepest layers of articular cartila

<正>Magnetic resonance imaging (MRI) has emerged as an invasive radiologic technique to assess and characterize cartilage lesions in the setting of injury and d

期刊

磁共振成像技术关节软骨自旋回波时间超短骨关节病技术评估FSE

Sulfolobus tokodaii RadA paralog, stRadC2, is involved in DNA recombination via interaction with Ra

Rad51/RadA paralogs found in eukaryotes and euryarchaea play important roles during recombination and repair,and mutations in one of the human Rad51 paralogs,Ra

期刊

DNA重组同源硫化RT-PCR分析DNA裂解紫外线照射DNA修复修复过程archaea Sulfolobus recombination

The role of Eph receptors in lens function and disease

其他学术论文