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目的探讨甘精胰岛素联合口服降糖药物对控制不佳的2型糖尿病患者的临床疗效。方法随机选取2009年11月至2010年11月在本院收治的血糖控制不佳2型糖尿病患者82例,随机分成观察组41例,对照组41例,对照组给予精蛋白合成人胰岛素联合口服药物治疗,观察组给予甘精胰岛素联合口服降糖药治疗,比较两组患者的临床疗效。结果治疗前两组在空腹血糖值、餐后血糖值没有显著性差异;治疗后两组在空腹血糖值和餐后血糖值上有显著性差异,P<0.05,有统计学意义。结论甘精胰岛素联合口服降糖药物治疗血糖控制不佳的2型糖尿病具有确切的临床疗效,值得临床推广使用。
Objective To investigate the clinical effects of glargine and oral hypoglycemic agents on patients with poorly controlled type 2 diabetes mellitus. Methods Totally 82 patients with type 2 diabetes with poor glycemic control admitted to our hospital from November 2009 to November 2010 were randomly divided into observation group (n = 41) and control group (n = 41). The control group was given protamine combined with insulin Drug treatment, observation group were given insulin glargine oral hypoglycemic agents, the clinical efficacy of two groups were compared. Results There was no significant difference in fasting blood glucose and postprandial blood glucose between the two groups before treatment. After treatment, there was significant difference between fasting blood glucose and postprandial blood glucose in both groups (P <0.05, statistically significant). Conclusion Glargine and oral hypoglycemic agents are effective in treating type 2 diabetes with poorly controlled blood glucose, which is worthy of clinical promotion.