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用免疫酶法测定278对新生儿及产妇血巨细胞病毒IgG,阳性率分别为98.20％和98.56％。生后30～50天复测64例可疑儿,IgG全部阳性,但滴度降低;2例巨细胞包涵体病滴度升高4倍以上。58例在2岁左右追踪检测,IgG阳性12例,IgM全部阴性;在5岁左右检测,IgG阳性23例,IgM阳性2例,并表现为巨细胞病毒单核细胞增多症样综合征。显示IgG在出生后逐渐消耗,又随年龄增长感染率上升而阳性者增多的规律,该文对IgG、IgM的检测与年龄之间的关系,孕前及孕期保健、胎儿生后的感染途径及免疫酶法的优点等进行了探讨。
The immunoenzymatic assay of 278 pairs of neonatal and maternal cytomegalovirus IgG, the positive rates were 98.20% and 98.56%. Sixty-four suspicious children were tested retrospectively 30 to 50 days after birth, all the IgG were positive, but the titer was decreased. The titer of 2 cases of giant cell inclusion body disease was increased more than 4 times. Fifty-eight cases were followed up for testing at 2 years old. IgM was negative in 12 cases and IgM was negative in all. IgM was positive in 23 cases and IgG was positive in 5 years old. The IgM was positive in 2 cases and showed cytomegalovirus mononucleosis syndrome. Shows the gradual consumption of IgG after birth, but also with the increase of age, the infection rate increases and the positive increase of the law, the article on the detection of IgG, IgM and the relationship between age, pre-pregnancy and pregnancy health, postnatal infection and immunization The advantages of enzymatic methods were discussed.