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[目的]探讨缺血修饰白蛋白(ischemia modified albumin,IMA)对急性冠脉综合征(acute coronary syn-drome,ACS)的早期诊断价值。[方法]确诊的ACS患者105例3h内取血测定IMA、肌钙蛋白I(cTnI)、肌酸激酶(CK)、肌酸激酶同功酶(CK-MB)和肌红蛋白(MYO),观察它们的变化水平。同时取65例健康体检者抽血测定IMA作对照组。[结果]病理组IMA水平明显高于对照组(P﹤0.01),ACS胸痛病人在胸痛发作就诊3h内抽血检测IMA阳性率达到84.8%,明显高于其他4种心肌标志物(P﹤0.01)。[结论]IMA对急性心肌缺血的早期诊断具有重要的临床意义,比其他4个心肌指标更为敏感。
[Objective] To investigate the value of ischemia modified albumin (IMA) in the early diagnosis of acute coronary syndrome (ACS). [Method] The serum levels of IMA, cTnI, CK, CK-MB and MYO in 105 patients diagnosed with ACS were measured within 3 hours. Observe their level of change. At the same time take 65 cases of healthy people blood test for IMA control group. [Results] The IMA level in the pathological group was significantly higher than that in the control group (P <0.01). The positive rate of IMA in blood tests for CHD patients with chest pain was significantly higher than that of the other 4 cardiac markers (P <0.01) ). [Conclusion] IMA has an important clinical significance in the early diagnosis of acute myocardial ischemia, which is more sensitive than the other 4 myocardial indexes.