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一个世纪前 ,Ｔｉｇｅｒｓｔｅｄ＆Ｂｅｒｇｍａｎｎ (1898)发现兔肾提取物中含有一种致血压增高的物质 ,嗣后证明体内存在肾素 -血管紧张素系统 (ｒｅｎｉｎ -ａｎｇｉｏｔｅｎｓｉｎｓｙｓｔｅｍ ,ＲＡＳ) ,为机体调节外周血管阻力和血压以及细胞外液水与电解质平衡最重要的?
A century ago, Tigersted & Bergmann (1898) found that rabbit kidney extracts contain a substance that causes increased blood pressure, subsequently confirming the presence of renin-angiotensin system (RAS) in the body that modulates peripheral vascular resistance and blood pressure And extracellular fluid and electrolyte balance the most important?