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目的 观察杏丁注射液治疗急性脑梗塞病人的疗效及治疗前后的血液流变学变化。方法选择发病72小时内的急性脑梗塞病人96例,随机分为治疗组48例和复方丹参对照组48例,分别用药14天。两组治疗前后评价神经功能缺损评分并检测血液流变学指标。结果 治疗组基本痊愈率31.25%,显著进步率39.58%,进步率8.33%,总有效率79.17%;对照组基本痊愈率12.50%,显著进步率18.75%;进步率31.25%,总有效率62.50%。两组比较有显著差异。治疗组用药后血液流变学较用药前也有显著差异(P<0.05)。结论:杏丁注射液治疗急性脑梗塞疗效显著,且无毒副作用。
Objective To observe the therapeutic effect of Xingding injection on patients with acute cerebral infarction and the changes of hemorheology before and after treatment. Methods Ninety-six patients with acute cerebral infarction within 72 hours after onset were randomly divided into treatment group (48 cases) and compound Salvia miltiorrhiza control group (48 cases), respectively, for 14 days. Neurological impairment scores and blood rheology were evaluated before and after treatment in both groups. Results The cure rate was 31.25% in the treatment group, with a significant improvement rate of 39.58%, a progressive rate of 8.33% and a total effective rate of 79.17%. The basic cure rate in the control group was 12.50% with a significant improvement rate of 18.75%, the progress rate was 31.25% and the total effective rate was 62.50% . There were significant differences between the two groups. Hemorrheology in the treatment group after medication was also significantly different (P <0.05). Conclusion: Xingding injection is effective in treating acute cerebral infarction with no toxic or side effects.