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目的观察用生理盐水稀释阿奇霉素后静滴不良反应的发生情况。方法将86例肺炎支原体感染的病人随机分成两组,各43例。一组用质量浓度为0.05g/mL的葡萄糖注射液250mL稀释阿奇霉素0.375g(Ⅰ组)后静滴,另一组用生理盐水250mL稀释阿奇霉素0.375g(Ⅱ组)后静滴。结果两组相比,Ⅱ组较Ⅰ组的不良反应轻。结论应用阿奇霉素静滴时用生理盐水稀释,不良反应明显下降。
Objective To observe the incidence of intravenous adverse reactions after diluted with azithromycin in physiological saline. Methods Totally 86 cases of Mycoplasma pneumoniae infection were divided into two groups at random, 43 cases each. A group of 250ml of glucose injection with mass concentration of 0.05g / mL was diluted with 0.375g of azithromycin (Group I) and the other group was intravenously diluted with 0.375g of azithromycin (250ml of normal saline). Results Compared with the two groups, the adverse reaction of group Ⅱ was lighter than that of group Ⅰ. Conclusion Azithromycin intravenous infusion of diluted, the adverse reaction decreased significantly.