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目的探讨胸部CT对重症肌无力患者胸腺病变的诊断价值。方法回顾性分析137例重症肌无力患者的胸腺CT影像及病理资料,分析CT影像及病理结果有无关联性。结果 137例重症肌无力患者胸腺异常共125例,占91.24%。CT诊断胸腺病变敏感度为86.40%,特异度为83.33%,准确度为86.13%,CT诊断结果和病理结果进行一致性检验:Kappa=0.427,P<0.001。结论 CT发现和诊断胸腺病变敏感度准确度较高,是诊断重症肌无力患者胸腺病变的较好方法。
Objective To investigate the diagnostic value of chest CT in thymus lesions in patients with myasthenia gravis. Methods The thymus CT images and pathological data of 137 patients with myasthenia gravis were retrospectively analyzed. The relationship between CT images and pathological findings was analyzed. Results There were 125 cases of thymus abnormalities in 137 cases of myasthenia gravis, accounting for 91.24%. The sensitivity, specificity and accuracy of CT diagnosis of thymus lesions were 86.40%, 83.33% and 86.13%, respectively. The concordance test between CT and pathology showed that Kappa = 0.427, P <0.001. Conclusion The accuracy of CT detection and diagnosis of thymus lesions is high, which is a good way to diagnose thymus lesions in patients with myasthenia gravis.