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皮肤为人体的保护层,并控制体内电解质和巨分子的向外运动,但极易受外界因素而损伤。柔润:皮肤的柔润,依赖于角质层含水的程度,含水量在10%以下时皮肤脆化,裂隙,引入刺激物及微生物。一般柔润剂能阻止因蒸发而损失的水份,使角质层自皮下吸取充分的水份。但厚层的石蜡能致阻塞,积水,拒水性的矽贡油(Silieone oils)为害更大。穿透性:皮肤的穿透作用在治疗上有极其重要的意义。穿透的途径有毛囊,皮脂腺,汗腺,和表皮直接穿透。毛囊中的分泌物皮脂可以供亲油性的药物透过,水溶性的药物
The skin is the protective layer of the human body and controls the outward movement of electrolytes and macromolecules in the body, but can be easily damaged by external factors. Gentle: Skin soft, depending on the degree of cuticle moisture, water content below 10% of the skin embrittlement, cracks, the introduction of irritants and microorganisms. The general emollient can prevent the loss of water due to evaporation, so that the stratum corneum from the skin to absorb adequate moisture. But thick paraffin can block, water, water repellent Silieone oils more damage. Penetration: The penetration of the skin is extremely important in the treatment. Pathways through the hair follicles, sebaceous glands, sweat glands, and the epidermis directly penetrate. Secretion of hair follicles in sebum for lipophilic drugs through, water-soluble drugs