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目的：探索药用丁基胶塞处理过程中参数控制与水分的关系，从而确定最佳参数的处理工艺。方法通过处理不同数量的药用丁基胶塞和改变处理的参数〔干燥时间，F0值(标准灭菌时间)〕，用干燥失重法检测经处理后的药用丁基橡胶塞水分残留量，统计分析各参数条件下的用丁基胶塞水分残留量。结果当F0值为15，干燥时间为60分钟时，胶塞的处理数量越大处理后的水分残留值越大；当胶塞的处理数量一定，F0值为15,干燥时间越长水分残留值越小；当胶塞的处理数量一定，干燥时间在60分钟时，F0值越大水分残留值越大。结论经综合分析选用F0值为15，干燥时间为60分钟的处理工艺既符合生产工艺要求又节约能源。“,”Objective:To explore the medicinal butyl rubbet stoppers processing parameter control and water relations, and thus determine the optimal parameters of the treatment process. Methods:The number of medicinal butyl rubbet stoppers to deal with different and changing parameters (drying time, F0 value), with dry weight loss was detected after treatment, the medicinal butyl rubber plug water residue Statistical analysis of the parameters under the conditions of water use butyl rubbet stoppers residues. Results:When the F0 value is 15, the drying time of 60 minutes, the stopper of the handle the greater number of residual values of the treated water in the larger; when a certain amount of processing rubber plug, F0 value is 15,The longer the drying time of water the smal er the residual value; when a certain amount of stopper processing, drying time of 60 minutes, F0 value is greater the larger the value of water left. Conclusion: After a comprehensive analysis of selected F0 value of 15, the drying time of 60 minutes of treatment processes are consistent with the requests for production processes and moisture content.