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为了确定在非洲乡村现场条件下将乙型肝炎疫苗纳入扩大的免疫计划(EPI)中的效果,作者在南非的文达地区(从乡村到小镇共7460平方公里)进行了乙型肝炎疫苗接种试验。该地区乙型肝炎发病率很高,男性成年黑人矿工的HBsAg携带率为8.7%。免疫对象是1989年在该地区出生的婴儿。免疫程序有两种:“早程序”是在出生时(0～14天)、出生后3个月(80～100天)和6个月(170～190天);“迟程序”是在出生后3个月、4个半月(125～145天)和6个月,以上称为“计划”免疫。未按上述时间免疫的称为“非计划”免疫。疫苗的剂量为10g,于大腿前外侧肌肉注射。用放射免疫法检测抗-HBs。执行这次免
To determine the effect of incorporating hepatitis B vaccine into an expanded immunization program (EPI) under rural site conditions in Africa, the authors conducted a Hepatitis B vaccination campaign in the Wenda region of South Africa (7460 km2 from village to town) test. The incidence of hepatitis B in the area is high, with adult black adults carrying HBsAg at a rate of 8.7%. The target of immunization was a baby born in the area in 1989. There are two types of immunization programs: “Early procedures” are at birth (0-14 days), 3 months after birth (80-100 days) and 6 months (170-190 days); “Late procedures” After 3 months, 4 and a half months (125 to 145 days) and 6 months, referred to above as “planned” immunizations. Immunizations that were not immunized at that time were called “unplanned” immunizations. Vaccine dose of 10g, in front of the thigh muscle injection. Anti-HBs were detected by radioimmunoassay. Execute this exemption